Depends on how you define big, but the easy answer is yes. We built our last company from nothing into a successful business. We were in the B2B space. Our customers when we sold included Apple, Xerox, Harley-Davidson,Chicago Bulls and many more. Never took a penny from VC's or Angels. When we closed the sale we owed nothing. We kept a line of credit, but never used it. When we closed it was for an eight figure amount. If you want to discuss more we are happy to set up a call.