It is possible to get AdSense approval for an HTML5 gaming site, but it is not guaranteed. Google AdSense has a strict set of guidelines for approving websites, and they are particularly cautious about approving sites that primarily consist of games. This is because games are often seen as low-value content, and they can also be difficult to monetize with ads.

However, there are a few things you can do to increase your chances of getting approved for AdSense:

Create high-quality games: Your games should be original, engaging, and bug-free. They should also be appropriate for your target audience.
Provide a good user experience: Your website should be easy to navigate and use. It should also be mobile-friendly.
Follow Google's AdSense policies: Make sure your website complies with all of Google's AdSense policies. This includes things like using appropriate ad placements, avoiding excessive ad blocking, and providing clear and concise privacy policies.
If you follow these tips, you will have a better chance of getting your HTML5 gaming site approved for AdSense. However, it is still important to remember that approval is not guaranteed.

Google is still approving new sites/networks, but they are being more selective than ever before. This is because they are trying to ensure that they are only approving high-quality sites that will provide a good experience for their users.

If you are serious about getting your HTML5 gaming site approved for AdSense, you should focus on creating high-quality content and providing a good user experience. This will give you the best chance of success.