Great question, when it comes to business federal taxing they are taxed as any other but as a virtual service provider (non-physical) every state has a different law on that. The general idea is that some states don't have an import or sales tax law and or out of state law - so technically speaking you may have to file taxes completely differently than any other business out there because each state may vary.
If you end up having to send a tech to that area, you may have to to file especially for that state - I'm not a tax professional and you may have to talk to a tax expert in this field. One of the tax preparers I trust is Perla, she owns a bookkeeping & tax service - tax@bluepearltax.com

As an example, when I file taxes because provide consultancy services that are not physical or create software that does not transfer to any physical object I don't have to file separately on states unless I happen to send something to them - then I would have to file for that state.