Well, ask yourself who would want to get in front of physicians?
I know a doctor who likes to go to Las Vegas for continuing education classes. There is a company there who offers this training.
I bet they'd love to either sponsor this kind of publication or make you a sales affiliate.
Really, the possibilities are endless. Once you've got the audience you can sell access.
Hope this helps.
How many people are on the list currently? Survey them and find out what they want, and then give it to them.
With my weekly curated newsletter I have used both sponsors and affiliate links. Sponsors work well in a narrow niche. I haven't had much luck with affiliates. Lots of clicks, little action. If you grow your list a bit, you will be able to find sponsors. You might not make as much money as you would like, though. A typical sponsor for a 2000 subcriber newsletter would expect to pay $50-$75.
I have found that the networking and status you achieve by curating a newsletter is more valuable.
There are several ways to do it.
1. sponsored newsletter content
2. dedicated e-blasts
3. in-newsletter advertising (banners within the newsletter content)
To name a few....
The first two options will likely require you to do some selling to advertisers. You would need to reach out to advertisers to generate interest in your list.
A simple way to start testing monetizing your list would be to sign up with a platform like https://liveintent.com/. They are an ad network for in-email advertising and will pay you to publish their ads in your newsletters. TechCrunch is a great example of a publisher who uses LiveIntent to monetize their daily newsletter.
How much you can earn from your list is a different topic. This will depend on the size of your list and your average open rates.
Hope this helps. I have a ton of experience monetizing email. I'd be happy to chat more.
A few thoughts:
CME - offer it for free to physicians with the catch they need to click through an ad to collect the CME. Selling the ad space is how you make money.
Specialty Specific - If you can focus the newsletter and CME on a specialty such as Radiology, Family Practice, etc, it will be much more appealing to a physician as opposed to a generic "medical" newsletter.
Click Local - If you can make the newsletter appear local it will also be more attractive to physicians. For instance, the Pacific Northwest Primary Care Montly update with free CME.