Depends on how you plan to get hired.

If you go the traditional route, which I say is akin to using stones and clubs in today's era, then you want your resume littered with keywords the HR departments of the large companies you're targeting are looking for.

If you want to do something that will take a bit more effort, but will get you a much better-fit role, create content and get it in front of the people who have the power to hire you.

I describe this second approach, which I have used to get four custom-made job offers and roles created just for me, in this radio interview:
https://www.youtube.com/watch?v=uW7VITbQPzU

Speaking plainly, there are a ton of "you IT guys" running around out there.

So your first job is to Stand Out.

Stand out to employers. If you don't do this, you never get the interview. They have to want to meet you. And a run-of-the-mill resume isn't likely to accomplish this.

Make a list of employers you'd like to work for. They should fit a profile: size, industry, top officer style, culture, etc.

Then create your content, and start marketing it--get it in front of the executive who has the power to hire you. LinkedIn is a good way to do this.

Here are a couple blog posts describing the rest of the process: http://www.salestactics.org/?s=job+hunting

Most of all, Have Fun! Yes, it is a job to get a job, but this way you are meeting the kind of people you want to meet, and showing them how you uniquely create value. As they keep seeing your content, their minds will begin to turn to "How can I make use of this person within my organization?" And that's when the seed of the idea of customizing a role for you appears.