I think ideally you would want smaller teams with bigger responsibilities, and accountability. You want them focused on the projects that provide the highest return.

The trick is to hire attitude and train for desired skills. Many places seem to do it backwards. They want a specific skill and forget that humans perform the work.

Teams will figure out their own dynamics and make things work. But you need to ensure that there is enough cross team interactions to ensure everybody is pulling in the same direction.

Also make sure the space is conducive to information exchange. At Tech Group, we used completely open spaces. No walls. So anybody could simply raise their head and communicate with anybody else. Conference room used for collaborative in-team tasks.