Would you start a new air transport service with only one airplane and one route?

If it's feasible then yes. But in this industry you really(!) need to know what you are doing! Many have tried and failed. Consider leasing an airplane first to see if there's demand and if the economics of the business make sense.

Good luck

Hi I definitely would give it a try however, partnerships and marketing will be very important. We all learn by taking chances. A lot of great companies started small. Let's talk on a call to discuss what a few of my past clients have done with their planes. You have a gold mine.