Yes, I've implemented the card based UI in a mobile app. In our particular case, cards work very well as we want the user to be forced to make a decision in the information we're presenting them but that kind of cognitive load is not something that all apps can or should be able to justify.
Implementing cards as a UX does force a lot of constraints if you're going to do it well but without knowing more about what you're designing, it's hard to give a helpful answer.
Happy to talk to you in a brief call and provide you some more contextually-relevant feedback.