How do I use B2B content marketing to get 100 appointments with enterprise-level marketing directors, VPs or CMOs?

A better question to ask in my polite opinion is what offer you make that cannot be refused, to paraphrase Godfather, and to whom. You have to analyze your competition and your business deeply. Then define what is the intersection of a large market, great proposition, ability to service, and unique value. I recommend focusing on the customer first and then on the product. If you want to flesh this out give me a call. All the best.

Content Marketing that you need to focus on is B2B. In both B2C and B2B customers become aware of your brand at various stages of the buying process; some accidentally and some through deliberate search with a potential purchase in mind. By understanding the process of buying you will understand the frame of mind and the changes to it, as the potential customer moves along the buying process. Generally, the buying process begins with an awareness of need. If you keep these facts in mind and you will surely succeed in content marketing.
Besides if you do have any questions give me a call: https://clarity.fm/joy-brotonath

I would start with the target customer and work backwards. The more bespoke/personalized the content the better. The other point is what's your point of differentiation.

1 - Check the incoterms and regulations for the territories that you want to ship ( Commerce chambers)
2 - Study the competition in those territories
3 - Customize your value proposition taking in account these
territories.
4 - Link with your target buyers via linkedin in those territories and try to understand if your value proposition is in line with what they need.
5 - Incorporate feedback and improve value proposition
6 - Start creating content targeting those territories and tag those people that you spoke already...

Content rich SEO practices. Let then get excited and come to you!