Who can I get help from in the CBD space?

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A substance that does not induce feelings of psychoactivity, cannabidiol, or “CBD” as it is most known, can be extracted from either the hemp or marijuana plants. Most products featured in CBD advertising strategies will be extracted from industrial hemp.
CBD falls into two main product segments:
• food grade, and
• therapeutic grade.
Based on a report by MarketWatch, therapeutic grade CBD constitutes the vast majority of market share, with this segment accounting for 59.90% of the market in 2018. Great growth opportunity in the cannabinoid space is represented by projected sales of nearly $12.8 billion in cannabis and $2 billion in hemp products during 2019 alone. To tap into this market, you must know these points:
1. Start at the Beginning: First, it is important to understand the difference between marijuana and hemp. The 2018 Farm Bill spelled it out: Hemp is a variety of the cannabis sativa plant which contains less than 0.3% THC (tetrahydrocannabinol or Δ-9 tetrahydrocannabinol) on a dry weight basis, while marijuana is the variety that has greater than 0.3% THC. The federal government prohibits the sale of marijuana, including concentrates and extracts of more than 0.3% THC. Conversely, hemp-derived cannabinoids are legal, and CBD (cannabidiol) products are being increasingly found in places like supermarkets and pharmacies, and as additives in food, beverages, or topical products. For now, only hemp-derived CBD is legal for sale in the United States.
2. Know the Market: A good understanding of the market is fundamental to developing one’s product. Some consumers may enjoy the taste and aroma of cannabis, whereas others may be curious about what a hemp-derived product can do for them but prefer to avoid the associated flavour or smell. If a marketer finds an audience comfortable with the flavours and aromas (i.e., the terpenes and terpenoids) of a hemp product, then the use of full-or broad-spectrum CBD may be advantageous, since terpenes and terpenoids remain present in the hemp extract (along with hemp/cannabis flavour and aroma). Likewise, CBD isolate is available to develop products without any hemp/cannabis aromas or taste.
3. Determine Dosing: Ascertain whether to make any types of claims regarding how much CBD is in a product, particularly per serving size. Existing products on the market which make claims about CBD content tend to focus on milligrams per serving; producers should implement quality systems to include testing. After testing some products, the FDA has recently issued warning letters due to findings that some companies provided less (or no) CBD than their labels claimed. Even without making claims, producers should confirm that the amounts included are appropriate and consistent for milligrams per serving.
4. Source the Best Possible Extract: In sourcing a hemp-derived CBD extract, producers need to confirm that it is safely compatible with laws regarding food, beverages or topicals. Producers should consult with suppliers to consider any types of risks (physical, chemical, microbial) associated with the extract, and assess the impacts on their products through risk analysis of the extract. Variables include pesticide residue, heavy metal uptake, microbial presence, residual solvents, and possibly mycotoxin. Check to see whether a supplier offers a certificate of analysis (COA) () to confirm the potency and risks of the CBD extract, and vouch for any claims made for the final product.
5. Identify the Best Way to Combine Ingredients: From full-spectrum to isolate, CBD extracts are oil-soluble. For food, beverages, or topical products that are oil-based, incorporation into the product should be straightforward, and mixed in such a way that the CBD is dispersed evenly through the entire product so that there are no “hot spots” of CBD in the finished good which can lessen its efficacy and lead to customer dissatisfaction. If a product is water-based or mostly water, then manufacturers should consider extra measures in making the oil and water mix, which can be done by dispersing the oil into the water by using a homogenizer or working the CBD into the water phase using emulsifiers to help prevent separation. The primary goal is to maintain stability and disperse the oil evenly into the product so that it does not separate or float to the surface like an Italian salad dressing. Also, producers should be mindful of pesticide-testing thresholds when choosing raw materials to mixed with clean cannabis extract or isolate. Often, pesticide thresholds for commonly used agricultural products (e.g., olive oil or strawberries) are higher than those required for cannabis products, so mixing without first testing every input could be a recipe for a failed product, despite one’s best efforts for cannabis inputs.
5. Create a Great Flavour Profile: Once a producer reliably incorporates CBD into their product, comes a focus on its flavour profile. If aiming for full spectrum flavour/aroma, producers can celebrate the fact by letting the taste and smell shine through. Conversely, an isolate should be of such low flavour and aroma profiles as to minimize any need of masking them. Nevertheless, using flavours such as citrus, cheese, berry, or sweet brown flavours (e.g., chocolate, almond, apple) might be preferable. Consultation with a flavour supplier is advisable. Taking a product from concept to commercialization involves a lot of work, especially for companies with less bandwidth or fewer resources to internally handle everything from start to finish. Tackling sourcing, applying food science, conducting safety and regulation checks, and other due diligence can be daunting without the right partners. It can be convenient to off-load many such needs to a supplier who has already taken many of the issues into account and made the CBD extract into an easily dispersible, water-soluble, food- and beverage-safe format. Producers can leverage the knowledge of such a supplier to help calculate usage rates and even work through where it may be most appropriate to add in one’s process. It may be intimidating to go through a new product development cycle with CBD in the mix, since the sourcing, regulatory environment, food science, and confirmation of product claims can be overwhelming. Yet, CBD represents an exciting new category with enormous growth potential, and countless big brands are racing into the space. While much of the product-development market can seem complex, there are undoubtedly many more CBD-infused products coming.
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it does not habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit. CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and in some cases, it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.

CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep. CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.
Since it is legal and has medicinal properties you can get more help about how to develop CBD and other rules in the following websites:
1. https://fas.org/sgp/crs/misc/R45525.pdf
2. https://medicalmarijuana.procon.org/states-with-legal-cannabidiol-cbd/
3. https://marijuana.procon.org/
4. https://medicalmarijuana.procon.org/legal-medical-marijuana-states-and-dc/
5. https://medicalmarijuana.procon.org/

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