No need to re-invent the wheel, especially considering that there are (hundreds of) thousands of people in your exact situation.

Check out a few of these:

http://www.forbes.com/sites/allbusiness/2014/09/26/which-e-commerce-platform-is-the-best-choice-for-your-online-store/

http://www.quora.com/Which-ecommerce-platform-should-we-use

http://www.cio.com/article/2449485/e-commerce/e-commerce-6-top-ecommerce-platforms-for-do-it-yourself-small-businesses.html

There are many more.

The short answer is that it depends. It depends on your tech skills, on whether you're happy with "out of the box" functionality or need anything custom, on what's your budget allocation, etc. etc. but the links above should give you a pretty good idea.

Hope this helps.

Bryan